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single-cell epigenomic reconstruction of developmental trajectories in human neural organoid systems from pluripotency

Fides Zenk, Jonas Simon Fleck, Sophie Martina Johanna Jansen, et al.



Selected by Manuel Lessi

2D and 3D multiplexed subcellular profiling of nuclear instability in human cancer

Shannon Coy, Brian Cheng, Jong Suk Lee, et al.



Selected by Jade Chan

Multi-pass, single-molecule nanopore reading of long protein strands with single-amino acid sensitivity

Keisuke Motone, Daphne Kontogiorgos-Heintz, Jasmine Wee, et al.



Selected by Benjamin Dominik Maier, Samantha Seah

Hibernating ribosomes tether to mitochondria as an adaptive response to cellular stress during glucose depletion

Olivier Gemin, Maciej Gluc, Michael Purdy, et al.



Selected by Barbora Knotkova

The loss of DNA polymerase epsilon accessory subunits POLE3-POLE4 leads to BRCA1-independent PARP inhibitor sensitivity

Hasan Mamar, Roberta Fajka-Boja, Mónika Mórocz, et al.



Selected by Audrey Noireterre

Digitize your Biology! Modeling multicellular systems through interpretable cell behavior

Jeanette A.I. Johnson, Genevieve L. Stein-O’Brien, Max Booth, et al.



Selected by Benjamin Dominik Maier et al.

Lincrnas enable germ cells differentiation by promoting PUF proteins condensation

Roni Falk, Noa Gilad, Hanna Achache, et al.



Selected by Umutcan Kaan Bozan et al.

PUFFFIN: A novel, ultra-bright, customisable, single-plasmid system for labelling cell neighbourhoods

Tamina Lebek, Mattias Malaguti, Alistair Elfick, et al.



Selected by Jennifer Ann Black

CRISPR-dependent base editing screens identify separation of function mutants of RADX with altered RAD51 regulatory activity

Madison B. Adolph, Atharv S. Garje, Swati Balakrishnan, et al.



Selected by Jessica Chevallier, Pierre Caron

A Phosphoproteomics Data Resource for Systems-level Modeling of Kinase Signaling Networks

Song Feng, James A. Sanford, Thomas Weber, et al.



Selected by Benjamin Dominik Maier

Similarity metric learning on perturbational datasets improves functional identification of perturbations

Ian Smith, Petr Smirnov, Benjamin Haibe-Kains



Selected by Benjamin Dominik Maier, Anna Foix Romero

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

Avi J. Samelson, Nabeela Ariqat, Justin McKetney, et al.



Selected by Kritika Mehta
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